The retention of water and sodium and hypertension caused by high salt diet will cause the glomerulus to be in the "three high" state (high pressure, high perfusion and high filtration), and make it difficult to control hypertension in patients with kidney disease, and increase the renal burden, thus accelerating the progress of renal failure. In addition, a high salt diet also poses the following risks to the kidneys:
——Aggravate proteinuria——
Foreign studies have shown that excessive salt intake can increase urinary protein excretion and significantly worsen renal function. Scientists have also found that reducing salt intake from 10 grams per day to 5 grams per day (currently recommended by the World Health Organization), combined with the use of ACEI (angiotensin II converting enzyme inhibitor) drugs, can significantly reduce urinary protein excretion.
——Aggravating renal osteopathy——
The metabolism of calcium and phosphorus in the human body is closely related to renal function, and many end-stage kidney disease patients have osteoporosis and renal bone disease caused by calcium and phosphorus metabolism disorders. Research has found that salt intake is one of the main dietary factors determining urinary calcium excretion. As sodium excretion increases in the urine, calcium also increases in the urine. Therefore, a high salt diet can lead to a negative balance of calcium and accelerate osteoporosis in kidney disease patients.
——Related to stone formation——
Calcium is the main component of most stones. As mentioned earlier, excessive salt intake can lead to an increase in urinary calcium, which provides a suitable breeding ground for the formation of stones. Therefore, a high salt diet is one of the important reasons for kidney stones.