There is a saying that men do not drink, but walk in the world for nothing. Wine is the essence of grain. The younger they drink, the more they love it. But do you know how much alcohol affects sperm? Do you know the harm of alcohol to sperm?
Drinking alcohol can directly affect the fertility of men, especially for those who drink too much, it is very easy to cause infertility in severe cases, or seriously affect the quality of sperm to cause damage to their next generation, and reduce the quality of their offspring. Scientific research shows that drinking alcohol has an impact on sperm: the plasma testosterone level drops by about 25% 10 to 16 hours after drinking, which shows that alcohol has a direct effect on the production of testosterone cells.
Spermatogenic cells exist in the supporting grid composed of sertoli cells, so sertoli cells play an important role in the support, nutrition, protection and metabolism of spermatogenic cells and in the generation, maturation and release of sperm.
Animal experiments showed that alcohol changed the shape of seminiferous tubules (sertoli cells+spermatogenic cells), reduced the diameter of the tubules, thinned the spermatogenic epithelium, and covered the same monolayer cells without secretory granules at the top. A large number of lipid droplets were gathered at the base of sertoli cells, and lipid droplets were also seen at the base of spermatocytes and sperm cells. The appearance of lipid droplets may be the direct effect of alcohol on the reproductive epithelium, or the sertoli cells engulf spermatogenic cells at all levels, or the alcohol destroys the synthesis of androgens in sertoli cells. Alcohol and its metabolites have cytotoxic and mutagenic effects on the metabolism of microsome system.
Sperm chromosome aberration and sister chromatin exchange can be seen in drinkers, which indicates that alcohol has a negative effect on the early development of sperm.
Studies on humans and animals have confirmed that alcohol can cause significant damage to sperm number, activity, morphology and function. Ethanol can be detected in sperm two hours after ingesting a moderate amount of alcohol (generally believed to be>30-90mL/d). The influence of alcohol on sperm is related to the age of starting drinking, the amount of drinking and the duration of drinking. Drinking alcohol before the age of 18, i.e. sexual maturity, has a greater impact on sperm than after the age of 18. Compared with the control group, the sperm count in the alcohol drinking group before sexual maturity decreased by 46.5%, and that in the alcohol drinking group after sexual maturity decreased by 18.9%; The sperm activity of the two groups decreased by 36.9% and 32.3% respectively. The author believes that the reproductive toxicity of alcohol is one of the causes of male infertility.
Effects of different ways of drinking on sperm
1. Excessive drinking
Excessive drinking can reduce men's ability, and can also damage sperm. Alcohol is the most common killer of men's fertility. Excessive drinking will lower the level of androgen. Excessive drinking can reduce the level of androgen by poisoning the testis; It can also cause abnormal liver function, reduce the inactivation of estrogen, and thus lead to the accumulation of estrogen, which relatively weakens the role of androgen, and makes men "difficult to invigorate the male spirit".
Fertility requires men's sperm to meet and combine with women's eggs. In this process, sperm need to release acrosin to dissolve the outer membrane of the egg. The high level of estrogen in men can make sperm release acrosin in advance before meeting the egg. When it is really needed, it cannot release this enzyme to destroy the outer membrane of the egg. Even if the sperm damaged by alcohol impregnates the egg, it is possible to give birth to children with low energy. Foreign countries call this kind of child "Sunday child", and think it is the bad result of pregnancy after couples drink a lot on weekends.
2. Long-term drinking
Long-term drinkers tend to lead to chronic alcoholism. Once chronic alcoholism occurs, patients will have testicular atrophy, resulting in a decline in semen quality. Research has found that it takes at least three months to recuperate once drunk to recover to the state before drunk. Experts believe that a man with a family planning plan can only conceive his wife at least three months after being drunk, so as to ensure the health of the fetus.
3. A small amount of alcohol
A small amount of alcohol does not affect the quality of sperm, but an excessive amount of alcohol will certainly affect the survival of sperm, because the main component of alcohol is ethanol, which acts as an anesthetic, and can quickly enter the tissues and cells of human body through blood circulation, thus affecting the quality of sperm
We all know that drinking alcohol has a great impact on health, not only on sperm. The harm of drinking to people can be seen from the route of drinking. First, the stomach. Alcohol will stimulate the gastric mucosa. People who drink often have a high incidence rate of stomach disease, followed by the liver. Many harmful substances in wine directly harm the liver. They also have an impact on blood pressure, the heart, and brain vesicles. It is very bad for memory and reflection of people who drink all the year round. So it's better to drink less wine.