A survey lasting over a decade has shown that men who work day and night shifts are 3.5 times more likely to develop prostate cancer than men who work long day shifts.
According to researchers, from 1988 to 1997, nearly 16000 men from 45 cities and villages across Japan were included in the survey, which aims to explore the relationship between working hours and the incidence of prostate cancer. Among all the men surveyed, 12756 were on a long-term day shift, 1184 were on a long-term night shift, and another 1966 were engaged in jobs that required them to work day and night shifts.
In the follow-up study, 55 people were ultimately diagnosed with prostate cancer, including 38 on day shift, 6 on night shift, and 11 on day and night shift. In addition, the researchers also comprehensively studied the patient's family history of prostate cancer and differences in age and region. The final statistical results show that men who work day and night shifts are 3.5 times more likely to develop prostate cancer than men who work day shifts for a long time; Statistically, there is almost no difference in the prevalence rate between men who work on night shifts for a long time and men who work on day shifts.
Researchers say that according to research so far, irregular shifts can disrupt the body's biological clock, reducing the secretion of melatonin, which inhibits the proliferation of prostate cancer cells. This may explain why men who work irregular hours are more likely to develop prostate cancer.